The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Dec. 12, 2016
Applicant:

Profusa, Inc., South San Francisco, CA (US);

Inventors:

William A. McMillan, La Honda, CA (US);

Natalie Wisniewski, San Francisco, CA (US);

Assignee:

Profusa, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 35/00 (2006.01); A61N 5/06 (2006.01); A61B 5/145 (2006.01); A61K 9/70 (2006.01); A61B 5/1459 (2006.01); A61M 5/142 (2006.01); A61M 11/00 (2006.01); A61M 37/00 (2006.01); A61K 9/00 (2006.01); A61N 5/067 (2006.01);
U.S. Cl.
CPC ...
A61N 5/062 (2013.01); A61B 5/1459 (2013.01); A61B 5/14503 (2013.01); A61B 5/14532 (2013.01); A61K 9/7038 (2013.01); A61M 5/14276 (2013.01); A61M 11/00 (2013.01); A61M 35/00 (2013.01); A61M 37/0015 (2013.01); A61K 9/0024 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0061 (2013.01); A61M 2205/52 (2013.01); A61M 2205/587 (2013.01); A61M 2230/005 (2013.01); A61M 2230/201 (2013.01); A61N 2005/067 (2013.01); A61N 2005/0626 (2013.01); A61N 2005/0645 (2013.01); A61N 2005/0652 (2013.01); A61N 2005/0661 (2013.01);
Abstract

The invention provides methods for directing a localized biological response of a mammalian body to an implant disposed within the body. In one embodiment, a delivery system is positioned outside the body and adjacent to the implant within the body. The delivery system comprises a first tissue response modifier effective for directing a localized biological response of the body to the implant. The tissue response modifier is nonsurgically delivered from the delivery system into the body in a quantity effective to direct the localized biological response of the body to the implant. The invention also provides an implant system for long-term use comprising an implant and nonsurgical means for delivering a tissue response modifier through the epidermis of the body, the tissue response modifier effective for directing a localized biological response of the body to the implant.


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