The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Apr. 06, 2016
Applicant:

Kyungpook National University Industry-academic Cooperation Foundation, Daegu, KR;

Inventors:

Jeong Soo Yoo, Daegu, KR;

Swarbhanu Sarkar, Daegu, KR;

Yeong Su Ha, Daegu, KR;

Woong Hee Lee, Daegu, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/10 (2006.01); C07B 59/00 (2006.01); A61K 51/04 (2006.01); A61K 49/00 (2006.01); C07F 1/08 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
A61K 49/106 (2013.01); A61K 49/0002 (2013.01); A61K 51/0478 (2013.01); A61K 51/0482 (2013.01); A61K 51/0491 (2013.01); A61K 51/0497 (2013.01); C07B 59/004 (2013.01); C07F 1/08 (2013.01); G01R 33/5601 (2013.01);
Abstract

Provided is a probe for detecting in vivo hydrogen sulfide, specifically, a probe for detecting hydrogen sulfide including a complex compound into which a radioactive isotope Cu is introduced. According to specific embodiments of the present disclosure, as a result of real-time observing animal models, in which hydrogen sulfide involved in various diseases is generated in a large quantity, through optical and nuclear medicine imaging, the probe for detecting hydrogen sulfide according to the present disclosure may selectively bind with hydrogen sulfide to provide images of a site where hydrogen sulfide has abnormally increased in a cell or a tissue, thereby detecting a disease in an unexpected site without affecting the anatomical properties of the body. Accordingly, the probe may be effectively used as a means for diagnosing diseases, such as a composition for imaging, an imaging method, etc.


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