The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Feb. 09, 2016
Applicant:

Entera Bio Ltd., Jerusalem, IL;

Inventors:

Gregory Burshtein, Modiin, IL;

Ariel Rothner, Jerusalem, IL;

Phillip M. Schwartz, Jerusalem, IL;

Hillel Galitzer, Yad Binyamin, IL;

Assignee:

Entera Bio Ltd., Jerusalem, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/29 (2006.01); A61K 38/22 (2006.01); A61K 31/19 (2006.01); A61K 31/05 (2006.01); A61K 31/20 (2006.01); A61K 9/00 (2006.01); A61K 31/166 (2006.01); A61K 38/55 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/29 (2013.01); A61K 9/0053 (2013.01); A61K 9/20 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2086 (2013.01); A61K 9/28 (2013.01); A61K 9/2886 (2013.01); A61K 31/05 (2013.01); A61K 31/166 (2013.01); A61K 31/19 (2013.01); A61K 31/20 (2013.01); A61K 38/22 (2013.01); A61K 38/55 (2013.01); A61K 45/06 (2013.01); A61K 2300/00 (2013.01);
Abstract

A pharmaceutical composition for oral administration is disclosed herein, comprising a therapeutically active agent, SNAC and at least one antacid compound. Further disclosed herein is a pharmaceutical composition unit dosage form for oral administration of a therapeutically active agent is provided herein, the unit dosage form comprising: a core comprising the therapeutically active agent and SNAC (sodium 8-N-(2-hydroxybenzoyl)aminocaprylate); and an external layer comprising at least one protective agent selected from the group consisting of an antacid compound and a protease inhibitor. Methods and uses utilizing the aforementioned pharmaceutical compositions, as well as methods and uses utilizing co-administration, by oral administration, of at least one antacid composition, and a composition comprising the therapeutically active agent and SNAC, are further disclosed herein, for use in treating a condition treatable by oral administration of the therapeutically active agent.


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