The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
May. 04, 2018
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Mark A. Hoon, Kensington, MD (US);
Santosh K. Mishra, Rockville, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 38/22 (2006.01); A01K 67/027 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); A61K 45/06 (2006.01); A61K 47/62 (2017.01); A61K 38/16 (2006.01); C12N 15/85 (2006.01); A61K 38/17 (2006.01); C07K 16/26 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 38/22 (2013.01); A01K 67/0276 (2013.01); A61K 38/164 (2013.01); A61K 38/1796 (2013.01); A61K 38/2242 (2013.01); A61K 45/06 (2013.01); A61K 47/62 (2017.08); C07K 16/26 (2013.01); C12N 15/1136 (2013.01); C12N 15/8509 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); A01K 2217/052 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/035 (2013.01); A01K 2267/0393 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/02 (2013.01);
Abstract
Disclosed is a method of treating, reducing, or preventing pruritis in a mammal, the method comprising administering at least one natriuretic polypeptide b (Nppb) blocking agent to a mammal in an amount effective to treat or prevent pruritis in the mammal. An in vitro method of identifying a compound that inhibits Nppb activity is also disclosed.