The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Mar. 02, 2017
Cedars-sinai Medical Center, Los Angeles, CA (US);
Satoshi Inoue, Beverly Hills, CA (US);
Hui Ding, Los Angeles, CA (US);
Eggehard Holler, Los Angeles, CA (US);
Keith L. Black, Los Angeles, CA (US);
Julia Y. Ljubimova, Studio City, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Abstract
Nanobiopolymeric conjugates based on biodegradable, non-toxic and non-immunogenic poly (β-L-malic acid) PMLA covalently linked to molecular modules that include morpholino antisense oligonucleotides (AONa), an siRNA or an antibody specific for an oncogenic protein in a cancer cell, and an antibody specific for a transferrin receptor protein, are provided. Methods for treating a cancer in subject with nanobiopolymeric conjugates are described.