The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Apr. 17, 2014
Applicant:

Shire Viropharma Incorporated, Lexington, MA (US);

Inventors:

Stanko Skrtic, Mölndal, SE;

Jörgen Johnsson, Helsingborg, SE;

Hans Lennernäs, Uppsala, SE;

Thomas Hedner, Gällstad, SE;

Gudmundur Johannsson, Halmstad, SE;

Assignee:

SHIRE VIROPHARMA INCORPORATED, Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/28 (2006.01); A61K 31/573 (2006.01); A61K 9/24 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/573 (2013.01); A61K 9/209 (2013.01); A61K 9/28 (2013.01); A61K 9/2031 (2013.01);
Abstract

The invention relates to glucocorticoid replacement therapy and provides pharmaceutical compositions and kits designed to deliver one or more glucocorticoids to a subject in need thereon in a manner that results in serum levels of the glucocorticoid that essentially mimic that of a healthy subject for a clinically relevant period of time. The pharmaceutical compositions and kits are prepared in such a way that a first part of one or more glucocorticoids is substantially immediately released and a second part of one or more glucocorticoids is released over an extended period of time of at least about 8 hours. The invention also relates to a method for treating diseases requiring glucocorticoid treatment such as in subjects having a glucocorticoid deficiency disorder.


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