The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Jun. 25, 2016
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

John P. Toscano, Glen Arm, MD (US);

Saghar Nourian, Columbia, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/515 (2006.01); A61K 31/352 (2006.01); A61K 31/4152 (2006.01); C07D 231/50 (2006.01); C07D 311/42 (2006.01); C07D 239/62 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/515 (2013.01); A61K 31/352 (2013.01); A61K 31/4152 (2013.01); A61P 9/00 (2018.01); C07D 231/50 (2013.01); C07D 239/62 (2013.01); C07D 311/42 (2013.01);
Abstract

N-substituted hydroxamic acids with carbon-based leaving groups as efficient HNO donors are disclosed. Pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions also are disclosed.


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