The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Dec. 02, 2016
The Scripps Research Institute, La Jolla, CA (US);
Leiden University, Leiden, NL;
Benjamin F. Cravatt, San Diego, CA (US);
Daisuke Ogasawara, San Diego, CA (US);
Andreu Viader, San Diego, CA (US);
Hui Deng, Leiden, NL;
Tom Van Der Wel, Voorburg, NL;
Marcelis Van Der Stelt, Utrecht, NL;
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
LEIDEN UNIVERSITY, Leiden, NL;
Abstract
Provided herein are triazole compounds and pharmaceutical compositions comprising said compounds useful as modulators of DAGL(α) and DAGL(β). In some embodiments, the compounds described herein are selective DAGL(α) inhibitors. Furthermore, the subject compounds and compositions are useful for the treatment of neurodegenerative or neuroinflammatory disease.