The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Oct. 08, 2015
University of South Australia, Adelaide, AU;
Central Adelaide Local Health Network Inc., Adelaide, AU;
Joanna Woodcock, Crafers, AU;
Angel Lopez, Medindie, AU;
Stuart Maxwell Pitson, Glenside, AU;
Michael Susithiran Samuel, North Adelaide, AU;
Carl Coolen, Salisbury South, AU;
University of South Australia, Adelaide, AU;
Central Adelaide Local Health Network Inc., Adelaide, AU;
Abstract
The present disclosure relates to modulators of 14-3-3 functionality and their use in methods and compositions for preventing and/or treating various diseases, conditions and states, such as cancer and healing of wounds. Certain embodiments of the present disclosure provide a method of preventing and/or treating a disease, condition or state in a subject associated with altered 14-3-3 protein functionality and/or which would benefit from altering 14-3-3 functionality, the method comprising administering to the subject an effective amount of an agent which inhibits dimerization of the 14-3-3 protein, thereby preventing and/or treating the disease, condition or state in the subject.