The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Oct. 23, 2015
Applicants:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Jinjun Shi, Boston, MA (US);

Xi Zhu, Qingdao, CN;

Omid C. Farokhzad, Waban, MA (US);

Xiaoding Xu, Malden, MA (US);

Yanlan Liu, Boston, MA (US);

Aude Thiriot, Brookline, MA (US);

Ulrich Von Andrian, Chestnut Hill, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/50 (2006.01); A61K 47/64 (2017.01); A61K 31/713 (2006.01); A61K 38/43 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 9/5021 (2013.01); A61K 9/5031 (2013.01); A61K 9/5078 (2013.01); A61K 9/5146 (2013.01); A61K 31/713 (2013.01); A61K 38/43 (2013.01); A61K 47/64 (2017.08); A61K 48/0041 (2013.01); Y02A 50/401 (2018.01); Y02A 50/475 (2018.01); Y02A 50/481 (2018.01);
Abstract

This invention relates to amphiphile-polymer particles comprising obtaining a first solution comprising a water-insoluble polymer, a payload and a first amphiphile in a water-miscible solvent; mixing the first solution with an aqueous second solution to form an aqueous composition comprising a particle comprising a water-insoluble polymeric core comprising the water-insoluble polymer; the payload; and the first amphiphile.


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