The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Apr. 27, 2016
Applicant:
Astellas Pharma Inc., Tokyo, JP;
Inventors:
Yumiko Suda, Tokyo, JP;
Toshiro Sakai, Tokyo, JP;
Ryo Kojima, Tokyo, JP;
Dal Oyama, Tokyo, JP;
Koji Nishimura, Tokyo, JP;
Kumi Naiki, Tokyo, JP;
Assignee:
ASTELLAS PHARMA INC., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 31/497 (2006.01); A61K 47/02 (2006.01); A61K 47/38 (2006.01); A61P 13/02 (2006.01); A61P 13/10 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2054 (2013.01); A61K 31/497 (2013.01); A61K 47/02 (2013.01); A61K 47/38 (2013.01); A61P 13/02 (2018.01); A61P 13/10 (2018.01);
Abstract
Disclosed is a pharmaceutical composition for oral administration, comprising 1-{5-[(5-{[(2R)-2-ethylpyrrolidin-1-yl]methyl}-4-[4-methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl)carbamoyl]pyrazin-2-yl}pyperidine-4-carboxylic acid, which is a compound having pH-dependent solubility, or a pharmaceutically acceptable salt thereof, and a cellulose derivative. In the pharmaceutical composition for oral administration, the solubility and absorbability of the drug are improved.