The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Feb. 03, 2017
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
Viktoria Gusarova, Pleasantville, NY (US);
Andrew J. Murphy, Croton-on-Hudson, NY (US);
Jesper Gromada, Scarsdale, NY (US);
Dayong Guo, Overland Park, KS (US);
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); A61K 49/00 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); A61K 49/0008 (2013.01); C07K 16/22 (2013.01); A01K 2207/15 (2013.01); A01K 2217/072 (2013.01); A01K 2217/206 (2013.01); A01K 2227/10 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0306 (2013.01); A01K 2267/0375 (2013.01); A61K 2039/505 (2013.01);
Abstract
Non-human animals, and methods and compositions for making and using the same, are provided, wherein said non-human animals comprise a humanization of an Angiopoietin-like protein 8 (ANGPTL8) gene. Said non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous ANGPTL8 locus so that said non-human animals express a human ANGPTL8 polypeptide.