The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2020
Filed:
Mar. 23, 2017
Applicant:
Alliance for Sustainable Energy, Llc, Golden, CO (US);
Inventors:
Yannick J. Bomble, Arvada, CO (US);
Michael E. Himmel, Littleton, CO (US);
Jeffrey Linger, Denver, CO (US);
Roman Brunecky, Arvada, CO (US);
John Aikens, La Grange, IL (US);
Assignee:
Alliance for Sustainable Energy, LLC, Golden, CO (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/18 (2006.01); C12N 11/00 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 15/62 (2006.01); C12N 11/18 (2006.01); C07K 14/195 (2006.01); C12N 11/06 (2006.01); C12P 7/42 (2006.01);
U.S. Cl.
CPC ...
C12P 7/18 (2013.01); C07K 14/195 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/0036 (2013.01); C12N 9/1022 (2013.01); C12N 11/00 (2013.01); C12N 11/06 (2013.01); C12N 11/18 (2013.01); C12N 15/62 (2013.01); C12P 7/42 (2013.01); C12Y 101/01006 (2013.01); C12Y 101/01076 (2013.01); C12Y 101/01086 (2013.01); C12Y 102/01 (2013.01); C12Y 102/01003 (2013.01); C12Y 106/03 (2013.01); C12Y 106/03001 (2013.01); C12Y 202/01006 (2013.01);
Abstract
Polypeptide scaffolds comprising enzymatic proteins are provided. The enzymatic polypeptide scaffolds comprise heterologous enzymes to form a heterologous metabolic pathway, and can be targeted to a substrate through a surface anchoring domain. The enzymatic polypeptide scaffolds leverage the high specificity and affinity protein/protein interaction between the cohesins and dockerins of microorganismal cellulosomes to form custom enzymatic arrays.