The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2020

Filed:

Dec. 16, 2015
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Feng Zhang, Cambridge, MA (US);

Le Cong, Cambridge, MA (US);

Fei Ran, Cambridge, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/00 (2006.01); C12N 15/90 (2006.01); C12N 9/22 (2006.01); C12N 15/63 (2006.01); C12N 15/10 (2006.01); A01K 67/027 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); A01K 67/0275 (2013.01); A61K 48/0058 (2013.01); A61K 48/0091 (2013.01); C12N 7/00 (2013.01); C12N 9/22 (2013.01); C12N 15/1082 (2013.01); C12N 15/63 (2013.01); C12N 15/86 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0312 (2013.01); A01K 2267/0331 (2013.01); A01K 2267/0362 (2013.01); A61K 48/00 (2013.01); C12N 2710/24144 (2013.01); C12N 2740/15043 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14152 (2013.01); C12Y 301/00 (2013.01);
Abstract

The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.


Find Patent Forward Citations

Zhang, Feng. (2020). Delivery and use of the crispr-cas systems, vectors and compositions for hepatic targeting and therapy (U.S. Patent No. 10577630). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10577630

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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