The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2020

Filed:

Mar. 20, 2017
Applicant:

Fresenius Kabi Ipsum S.r.l., Cassina de' Pecchi (Milan), IT;

Inventors:

Walter Cabri, Milan, IT;

Antonio Ricci, Pescara, IT;

Jacopo Zanon, Venice, IT;

Saswata Lahiri, Ghaziabad, IN;

Govind Singh, Ghaziabad, IN;

Shivaji Haribhau Shelke, Maharashtra, IN;

Tapanjyoti Biswal, Haryana, IN;

Nitin Kumar, Delhi, IN;

Madan Singh, Delhi, IN;

Assignee:

Fresenius Kabi iPSUM S.r.l., Cassina de' Pecchi (Milan), IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/16 (2006.01); C07C 323/52 (2006.01); C07C 319/12 (2006.01); C08B 37/00 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0012 (2013.01); C07C 319/12 (2013.01); C07C 323/52 (2013.01); C08B 37/0003 (2013.01);
Abstract

The present application provides an improved process for the preparation of sugammadex by reacting a salt of 3-mercapto propionic acid with 6-per-deoxy-6-per-halo-γ-cyclodextrin in a suitable organic solvent. This application also provides crystalline form of a salt of 3-mercapto propionic acid, preferably di sodium salt of 3-mercapto propionic acid and its use for the preparation of sugammadex, whereas formula (I) shows the sodium salt of sugammadex.


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