The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2020
Filed:
Mar. 12, 2018
Effector Therapeutics, Inc., San Diego, CA (US);
Justin T. Ernst, San Diego, CA (US);
Siegfried H. Reich, La Jolla, CA (US);
Paul A. Sprengeler, Escondido, CA (US);
Chinh Viet Tran, San Diego, CA (US);
Garrick Kenneth Packard, San Diego, CA (US);
Alan X. Xiang, Irvine, CA (US);
Christian Nilewski, La Jolla, CA (US);
Theo Michels, San Diego, CA (US);
eFFECTOR Therapeutics, Inc., San Diego, CA (US);
Abstract
The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. For Formula I compounds X, Y, R, R, R, R, R, Rand Rare as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4A and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.