The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2020
Filed:
Aug. 25, 2016
Constellation Pharmaceuticals, Inc., Cambridge, MA (US);
Brian K. Albrecht, Cambridge, MA (US);
Alisha Arrigo, Boulder, CO (US);
Donald Corson, Boulder, CO (US);
Victor S. Gehling, Somerville, MA (US);
Bruno Patrice Haché, Longmont, CO (US);
Jean-Christophe Harmange, Andover, MA (US);
Jonathan Lane, Longmont, CO (US);
Constellation Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The present disclosure relates to a crystalline Forms A, B, and C of (R)—N-((4-methoxy-6-methyl-2-oxo-1,2-di-hydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide, each of which are useful as modulators the activity of histone methyl modifying enzymes. The present disclosure also provides pharmaceutically acceptable compositions comprising the crystalline forms and methods of using said compositions in the treatment of various disorders.