The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2020

Filed:

Dec. 18, 2017
Applicant:

Duke University, Durham, NC (US);

Inventors:

Warren M. Grill, Durham, NC (US);

Bryan Howell, Durham, NC (US);

Shivanand P. Lad, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/05 (2006.01); A61N 1/36 (2006.01); G16H 20/30 (2018.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
A61N 1/0551 (2013.01); A61N 1/05 (2013.01); A61N 1/36 (2013.01); A61N 1/36071 (2013.01); A61N 1/36128 (2013.01); G16H 20/30 (2018.01); G16H 50/50 (2018.01); A61N 1/36125 (2013.01);
Abstract

Systems, methods, and devices are disclosed for optimizing patient-specific stimulation parameters for spinal cord stimulation. A patient-specific anatomical model is developed based on a pre-operative image, and a patient-specific electrical model is developed based on the anatomical model. The inputs to the electric model are chosen, and the model is used to calculate a distribution of electrical potentials within the modeled domain. Models of neural elements are stimulated with the electric potentials and used to determine which elements are directly activated by the stimulus. Information about the models inputs and which neural elements are active is applied to a cost function. Based on the value of the cost function, the inputs to the optimization process may be adjusted. Inputs to the optimization process include lead/electrode array geometry, lead configuration, lead positions, and lead signal characteristics, such as pulse width, amplitude, frequency and polarity.


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