The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2020

Filed:

Feb. 01, 2018
Applicant:

Boehringer Ingelheim Vetmedica, Inc., St. Joseph, MO (US);

Inventors:

Marc Allan Eichmeyer, Bondurant, IA (US);

Gregory Paul Nitzel, Paw Paw, MI (US);

Merrill Lynn Schaeffer, St. Joseph, MO (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); G01N 33/569 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); G01N 33/56983 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55566 (2013.01); C12N 2710/14143 (2013.01); C12N 2710/14163 (2013.01); C12N 2750/10022 (2013.01); C12N 2750/10034 (2013.01); C12N 2750/10051 (2013.01); C12N 2770/10034 (2013.01);
Abstract

An improved method for recovering the protein expressed by open reading frame 2 from porcine circovirus type 2 is provided. The method generally involves the steps of transfecting recombinant virus containing open reading frame 2 coding sequences into cells contained in growth media, causing the virus to express open reading frame 2, and recovering the expressed protein in the supernate. This recovery should take place beginning approximately 5 days after infection of the cells in order to permit sufficient quantities of recombinant protein to be expressed and secreted from the cell into the growth media. Such methods avoid costly and time consuming extraction procedures required to separate and recover the recombinant protein from within the cells.


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