The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2020
Filed:
Oct. 27, 2017
Applicant:
Hough Ear Institute, Oklahoma City, OK (US);
Inventors:
Richard D. Kopke, Oklahoma City, OK (US);
Wei Li, Edmond, OK (US);
Assignee:
Hough Ear Institute, Oklahoma City, OK (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); C07K 14/475 (2006.01); A61K 38/07 (2006.01); A61K 31/185 (2006.01); A61K 31/198 (2006.01); A61K 31/41 (2006.01); A61K 38/06 (2006.01); A61K 31/221 (2006.01); A61K 38/08 (2019.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 31/185 (2013.01); A61K 31/198 (2013.01); A61K 31/221 (2013.01); A61K 31/41 (2013.01); A61K 38/063 (2013.01); A61K 38/07 (2013.01); C07K 14/475 (2013.01); A61K 38/085 (2013.01);
Abstract
Disclosed here is a method for enhancing synaptogenesis and/or neuritogenesis, reducing neurodegeneration, and/or reducing accumulation or aggregation of Tau proteins in a subject suffering from cochlear synaptopathy or vestibular synaptopathy or a central nervous system disease or condition, comprising administering to said subject in need thereof an effective amount of 2,4-disulfonyl α-phenyl tertiary butyl nitrone (2,4-DSPBN) or a pharmaceutically acceptable salt thereof. The method may further comprise administrating N-acetylcysteine (NAC) to the subject.