The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2020
Filed:
Oct. 15, 2018
Shyam S. Mohapatra, Lutz, FL (US);
Alya Limayem, Tampa, FL (US);
Shyam S. Mohapatra, Lutz, FL (US);
Alya Limayem, Tampa, FL (US);
University of South Florida, Tampa, FL (US);
Abstract
A broad-based remediation mechanism against MRFs and alternative fecal indicators such as multidrug resistant, including nanotechnology formulations and methodologies that may be used to develop novel treatment strategies against certain drug resistant bacterial strains. The current invention relates to the treatment of drug resistant bacteria from nosocomial infections, for example in hospitals and in food animals. The invention uses hybrid nanomaterials comprising oligo-chitosan and zinc oxide formulated as nanoparticles and micelles. The inventors unexpectedly found unique properties of very small oligomers of chitosan that effectively treat multi-drug resistant bacteria without compromising the balance of the beneficial flora in the physiological and ecological microenvironments in a host. Also, the combination of chitosan with zinc oxide demonstrated synergistic and unexpected effects in remediation of important food-borne bacteria including the resistant types.