The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
Sep. 29, 2014
Trustees of Boston University, Boston, MA (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Jerome S. Brody, Boston, MA (US);
Avrum Spira, Newton, MA (US);
Adam Gustafson, Portland, OR (US);
Andrea Bild, Salt Lake City, UT (US);
Trustees of Boston University, Boston, MA (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Abstract
The invention provides the identification of oncogenic pathways activated in cytologically normal airway cells of individuals having or at risk of having lung disease, as well as specific gene expression patterns (biomarkers) associated with pathway activation. These biomarkers and pathways may provide prognostic and/or diagnostic indicators in lung disease, e.g., lung cancer. Additionally, these pathways and biomarkers may provide therapeutic targets for the treatment of lung disease, as well as markers for the assessment of treatment efficacy.