The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
Jun. 14, 2018
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
Gabor Butora, Martinsville, NJ (US);
Matthew Stanton, Needham, MA (US);
Thomas Steele, Upton, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/10 (2006.01); C07H 21/02 (2006.01); C07D 473/18 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1089 (2013.01); C07D 473/18 (2013.01); C07D 473/34 (2013.01); C07H 21/02 (2013.01); C12N 2310/313 (2013.01); C12N 2310/314 (2013.01); C12N 2310/317 (2013.01); C12N 2310/3125 (2013.01);
Abstract
The present disclosure relates to cap analogs, which can result in high levels of capping efficiency and transcription and improved translation efficiencies. The present disclosure also relates to methods useful for preparing cap analogs and using mRNA species containing such analogs, as well as kits containing the cap analogs.