The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
Oct. 23, 2015
Applicant:
Kaneka Corporation, Osaka-shi, Osaka, JP;
Inventor:
Tozo Nishiyama, Takasago, JP;
Assignee:
KANEKA CORPORATION, Osaka-Shi, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); C12N 15/09 (2006.01); C12N 1/19 (2006.01); C07K 16/00 (2006.01); C12P 21/08 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
C07K 16/241 (2013.01); C12N 15/815 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01);
Abstract
It is an object of the present invention to provide a method for producing a low-molecular-weight antibody such as a Fab-type antibody, using yeast as a host, wherein the method is able to produce the low-molecular-weight antibody with high productivity. According to the present invention, there is provided a gene comprising a nucleotide sequence encoding an amino acid or an amino acid sequence capable of increasing the secretion amount of a Fab-type antibody at the 3'-terminus of a nucleotide sequence encoding the amino acid sequence of the Fd chain or L chain of an antibody.