The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
Mar. 27, 2017
Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;
Centaurus Biopharma Co., Ltd., Beijing, CN;
Lianyungang Runzhong Pharmaceutical Co., Ltd., Lianyungang, CN;
Shulong Wang, Beijing, CN;
Kuncheng Chen, Beijing, CN;
Xijie Liu, Beijing, CN;
Yuandong Hu, Beijing, CN;
Bo Liu, Beijing, CN;
Yong Peng, Beijing, CN;
Hong Luo, Beijing, CN;
Yongxin Han, Beijing, CN;
Shanchun Wang, Lianyungang, CN;
Mei Liu, Lianyungang, CN;
Hongjiang Xu, Lianyungang, CN;
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., Jiangsu, CN;
CENTAURUS BIOPHARMA CO., LTD., Beijing, CN;
LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD., Jiangsu, CN;
Abstract
The present invention belongs to the field of pharmaceutical chemistry, and relates to a substituted pyrrolopyrimidine CDK inhibitor, in particular to a compound as shown in formula I or a pharmaceutically acceptable salt or solvate thereof, as well as a preparation method thereof and a pharmaceutical composition thereof. The present invention also relates to the use of the compound and the pharmaceutical composition thereof in the preparation of a drug for treating diseases associated with CDK inhibition. The compound according to the present invention has a marked inhibitory effect on CDK, excellent drug absorption and significantly superior oral absorption effect.