The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
Jul. 19, 2018
Applicant:
Surface Logix, Llc, Cambridge, MA (US);
Inventors:
Alessandra Bartolozzi, Somerville, MA (US);
Stewart Campbell, Framingham, MA (US);
Hope Foudoulakis, Framingham, MA (US);
Brian Kirk, Sudbury, MA (US);
Siya Ram, Winchester, MA (US);
Paul Sweetnam, Marblehead, MA (US);
Hemalatha Seshadri, Waltham, MA (US);
Assignee:
SURFACE LOGIX, LLC, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); B82Y 30/00 (2011.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); B82Y 30/00 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01);
Abstract
The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.