The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2020

Filed:

Jun. 05, 2018
Applicant:

Epigen Biosciences, Inc., San Diego, CA (US);

Inventors:

Graham Beaton, San Diego, CA (US);

Fabio C. Tucci, San Diego, CA (US);

Satheesh B. Ravula, San Diego, CA (US);

Chandravadan R. Shah, San Diego, CA (US);

Hiep Luu, San Marcos, CA (US);

Assignee:

EPIGEN BIOSCIENCES, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 261/14 (2006.01); C07D 231/38 (2006.01); C07D 231/52 (2006.01); C07D 233/88 (2006.01); C07D 401/04 (2006.01); C07D 239/42 (2006.01); C07D 413/04 (2006.01); C07D 263/48 (2006.01);
U.S. Cl.
CPC ...
C07D 261/14 (2013.01); A61K 31/415 (2013.01); C07D 231/38 (2013.01); C07D 231/52 (2013.01); C07D 233/88 (2013.01); C07D 239/42 (2013.01); C07D 263/48 (2013.01); C07D 401/04 (2013.01); C07D 413/04 (2013.01);
Abstract

A method for treating a lysophosphatidic acid-dependent disease or condition in a subject in need thereof is provided. The method includes administering to the subject a therapeutically effective amount of a heterocyclic compound. The heterocyclic compound is a lysophosphatidic acid receptor ligand. Lysophosphatidic acid-dependent diseases and conditions include diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain.


Find Patent Forward Citations

Loading…