The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2020

Filed:

Jun. 29, 2016
Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Takashi Ouchi, Osaka, JP;

Giho Goh, Daejeon, KR;

Sunmi Kim, Daejeon, KR;

Jinsoon Choi, Daejeon, KR;

Hunsoo Park, Daejeon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01J 8/02 (2006.01); B01J 21/04 (2006.01); B01J 23/44 (2006.01); C07B 31/00 (2006.01); C07B 41/06 (2006.01); C07C 253/30 (2006.01); C07C 255/28 (2006.01); C07D 207/36 (2006.01); C07B 61/00 (2006.01); B01J 29/08 (2006.01);
U.S. Cl.
CPC ...
C07D 207/36 (2013.01); B01J 8/0278 (2013.01); B01J 21/04 (2013.01); B01J 23/44 (2013.01); B01J 29/08 (2013.01); C07B 31/00 (2013.01); C07B 41/06 (2013.01); C07B 61/00 (2013.01); C07C 253/30 (2013.01); C07C 255/28 (2013.01); B01J 2523/67 (2013.01); B01J 2523/68 (2013.01); B01J 2523/69 (2013.01); B01J 2523/824 (2013.01); B01J 2523/828 (2013.01); B01J 2523/847 (2013.01);
Abstract

The present invention provides a production method of a 3-cyanopyrrole compound possibly useful as an intermediate for pharmaceutical products. A production method of compound (II) including subjecting compound (I) to a reduction reaction, in which the aforementioned reduction reaction is continuous hydrogenation reaction in a fixed bed reactor filled with a supported metal catalyst. A production method of compound (III) including subjecting compound (I) to a reduction reaction followed by a cyclization reaction, in which the aforementioned reduction reaction is continuous hydrogenation reaction in a fixed bed reactor filled with a supported metal catalyst.


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