The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
Aug. 22, 2017
Applicant:
Human Biomolecular Research Foundation, San Diego, CA (US);
Inventors:
John R. Cashman, San Diego, CA (US);
Jaroslaw Kalisiak, San Diego, CA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 251/40 (2006.01); C07C 279/12 (2006.01); C07C 257/12 (2006.01); C07C 257/14 (2006.01); C07C 257/18 (2006.01); C07D 239/06 (2006.01); C07D 249/04 (2006.01); C07D 233/24 (2006.01);
U.S. Cl.
CPC ...
C07C 251/40 (2013.01); C07C 257/12 (2013.01); C07C 257/14 (2013.01); C07C 257/18 (2013.01); C07C 279/12 (2013.01); C07D 233/24 (2013.01); C07D 239/06 (2013.01); C07D 249/04 (2013.01);
Abstract
The invention describes pharmaceutical agents capable of crossing the blood brain barrier to protect against organophosphate pesticides and nerve agents or other electrophiles by reactivating inhibited cholinesterase (i.e., acetylcholinesterase and butyrylcholinesterase) and other proteins in the peripheral and central nervous system.