The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2020

Filed:

Jun. 14, 2017
Applicant:

Cellply S.r.l., Bologna, IT;

Inventors:

Massimo Bocchi, Sasso Marconi, IT;

Andrea Faenza, Bologna, IT;

Laura Rocchi, Bologna, IT;

Dario Biscarini, Bologna, IT;

Nicola Pecorari, Bologna, IT;

Assignee:

CELLPLY S.R.L., Bologna, IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); B01L 3/00 (2006.01); B01L 3/02 (2006.01); G01N 35/10 (2006.01); G01N 15/14 (2006.01); G06K 9/00 (2006.01); G01N 1/30 (2006.01); G01N 1/31 (2006.01); G06T 7/00 (2017.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50273 (2013.01); B01L 3/0275 (2013.01); B01L 3/502715 (2013.01); G01N 1/30 (2013.01); G01N 1/31 (2013.01); G01N 15/1463 (2013.01); G01N 15/1484 (2013.01); G01N 33/5011 (2013.01); G01N 35/10 (2013.01); G01N 35/1011 (2013.01); G06K 9/00147 (2013.01); G06T 7/0012 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/06 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0861 (2013.01); B01L 2400/04 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1493 (2013.01); G01N 2015/1497 (2013.01); G01N 2500/10 (2013.01); G06T 7/0014 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30072 (2013.01); G06T 2207/30242 (2013.01);
Abstract

Methods are provided for the large-scale high-content analysis of biological samples. In some embodiments, the methods are implemented in a reversed open microwell system that includes an array of open microwells, at least one microchannel, at least one input port and at least one output port. In certain embodiments, the reversed open microwell system can be inserted in an automated management system which includes an incubator at controlled temperature, humidity and CO2 levels, a fluid dispensing system, and is capable of phase-contrast and fluorescence image acquisition. Also provided are kits for introducing fluids into a microfluidic device, and systems for discharging one or more fluids in a microfluidic device.


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