The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2020

Filed:

Dec. 19, 2014
Applicant:

Kent State University, Kent, OH (US);

Inventors:

Elda Hegmann, Kent, OH (US);

Torsten Hegmann, Kent, OH (US);

Yunxiang Gao, Kent, OH (US);

Assignee:

KENT STATE UNIVERSITY, Kent, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/56 (2006.01); C09K 19/38 (2006.01); A61L 27/18 (2006.01); C08G 63/682 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); C08J 9/26 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61L 27/3834 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); C08G 63/6822 (2013.01); C08J 9/26 (2013.01); C09K 19/3833 (2013.01); C09K 19/3838 (2013.01); C12N 5/0062 (2013.01); A61L 2300/63 (2013.01); A61L 2400/00 (2013.01); A61L 2400/08 (2013.01); C08J 2201/0442 (2013.01); C08J 2207/10 (2013.01); C08J 2367/04 (2013.01); C09K 2219/00 (2013.01); C12N 2533/30 (2013.01); C12N 2537/10 (2013.01);
Abstract

A polymeric scaffold contains pendant liquid crystal side chains and has fully interconnected pores. Such a polymeric scaffold will preferably be 3D in nature and elastomeric, biocompatible and biodegradable. Such 3D liquid crystal elastomer (LCE) scaffolds can be used for various biomedical applications, including cell culture applications. A method for the production of such a polymeric scaffold containing liquid crystals and having interconnected pores is also disclosed that uses a metal foam sacrificial template as a scaffold to produce the polymeric smart response scaffold of the present invention. Consistent and controlled pore sizes result from etching the sacrificial metal foam template away from the polymeric scaffold, permitting the incorporation of growth factors, when needed, for enhancing cell viability and proliferation.


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