The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2020
Filed:
May. 13, 2016
Applicant:
Agenus Inc., Lexington, MA (US);
Inventors:
Daniel Lewis Levey, Boston, MA (US);
John Christopher Castle, Mainz, DE;
Assignee:
AGENUS INC., Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/39 (2006.01); C07K 14/47 (2006.01); C07K 14/74 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/39 (2013.01); C07K 14/4748 (2013.01); C07K 14/70539 (2013.01); C12Q 1/6886 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55533 (2013.01); A61K 2039/55577 (2013.01); A61K 2039/575 (2013.01); C07K 2319/33 (2013.01);
Abstract
Provided are compositions useful as therapeutic vaccines (e.g., cancer vaccines), and methods of producing such compositions. The compositions disclosed herein generally employ a stress protein and at least one synthetic peptide, which may be a phosphopeptide or phosphopeptide mimetic, comprising a cancer-specific mutation present in a patient's cancer.