The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Nov. 11, 2016
Applicant:

Microsoft Technology Licensing, Llc, Redmond, WA (US);

Inventors:

Daniel Lo, Bellevue, WA (US);

Eric Chung, Woodinville, WA (US);

Kalin Ovtcharov, Kirkland, WA (US);

Ravindra Pandya, Clyde Hill, WA (US);

David Heckerman, Santa Monica, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 33/50 (2006.01); G16B 30/00 (2019.01); G06F 7/02 (2006.01);
U.S. Cl.
CPC ...
G16B 30/00 (2019.02); G06F 7/02 (2013.01);
Abstract

Comparisons between two nucleotide sequences can be performed by customized integrated circuitry that can implement a Smith Waterman analysis in series, as opposed to the parallel implementations known in the art. Series performance enables such customized integrated circuitry to take advantage of optimizations, including enveloping thresholds that demarcate between cells of a two-dimensional matrix for which nucleotide comparisons are to be performed, and cells of the two-dimensional matrix for which no such comparison need be performed, and, instead, a value of zero can simply be entered. Additionally, such customized integrated circuitry facilitates the combination of multiple control units, each directing the comparison of a unique pair of nucleotides, with a single calculation engine that can generate values for individual cells of the two-dimensional matrices by which such pairs of nucleotides are compared.


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