The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Feb. 10, 2016
Applicant:
Public University Corporation Nagoya City University, Nagoya-shi, Aichi, JP;
Inventors:
Yutaka Kondo, Nagoya, JP;
Keisuke Katsushima, Nagoya, JP;
Assignee:
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY, Nagoya-Shi, Aichi, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01); A61K 48/00 (2006.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01); A61K 31/7125 (2006.01); A61K 35/76 (2015.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 31/7125 (2013.01); A61K 35/76 (2013.01); A61K 48/00 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3519 (2013.01);
Abstract
This invention provides a composition and a method for treating or preventing a subject having a tumor that more highly expresses a TUG1 gene than in normal tissues (e.g., brain tumor, breast cancer, colon cancer, prostate cancer, liver cancer, lung cancer, leukemia, or lymphoma), which composition comprises, as an active ingredient, a nucleic acid that inhibits the high expression of the TUG1 gene in tumor stem cells.