The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Nov. 13, 2018
Applicant:
H. Lundbeck A/s, Valby, DK;
Inventors:
Jan Torleif Pedersen, Valby, DK;
Lars Østergaard Pedersen, Valby, DK;
Justus Claus Daechsel, Valby, DK;
Ayodeji Abdur-rasheed Asuni, Valby, DK;
Nina Helen Rosenqvist, Valby, DK;
Christiane Volbracht, Valby, DK;
Lone Helboe, Valby, DK;
Anders Brandt Elvang, Valby, DK;
Florence Sotty, Valby, DK;
Søren Christensen, Valby, DK;
Jeffrey B. Stavenhagen, Valby, DK;
Assignee:
H. Lundbeck A/S, Valby, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 39/395 (2006.01); G01N 33/68 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/395 (2013.01); A61K 49/00 (2013.01); G01N 33/6896 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01);
Abstract
The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.