The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Apr. 08, 2011
Álvaro Segura Ruiz, San José, CR;
Mariángela Vargas Arroyo, San José, CR;
Guillermo León Montero, Alajuela, CR;
Mauren Villalta Arrieta, San José, CR;
María Herrera Vega, Cartago, CR;
Yamileth Angulo Ugalde, San José, CR;
Álvaro Segura Ruiz, San José, CR;
Mariángela Vargas Arroyo, San José, CR;
Guillermo León Montero, Alajuela, CR;
Mauren Villalta Arrieta, San José, CR;
María Herrera Vega, Cartago, CR;
Yamileth Angulo Ugalde, San José, CR;
UNIVERSIDAD DE COSTA RICA, San Jose, CR;
Abstract
A method for producing injectable pharmaceutical formulations of blood-derived protein materials includes the steps of fractioning the source material in a polymer/salt aqueous two-phase system in the presence of phenol, purifying the top phase of the system by means of precipitation with caprylic acid and purifying the bottom phase by means of thermocoagulation, increasing the purity of the materials in both phases through chromatography, removing viral particles by means of the nanofiltration of both preparations, and formulating, stabilizing, and packaging the resulting materials.