The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Oct. 24, 2016
Applicant:

Mallinckrodt Pharma Ip Trading D.a.c., an Irish Designated Activity Company, Dublin, IE;

Inventors:

Abraham Bout, Moerkapelle, NL;

Joseph Grimbergen, Lisse, NL;

Jacob Koopman, Leiderdorp, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/75 (2006.01); C07H 21/04 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C07K 14/75 (2013.01);
Abstract

The present invention relates to nucleotide sequences encoding a fibrinogen alpha, beta or gamma chain. The sequences are optimized for expression in a eukaryotic cell culture system. Such optimized nucleotide sequences allow for the efficient expression of recombinant fibrinogen and variants thereof in intact form in a eukaryotic cell culture system.


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