The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Aug. 02, 2017
Applicant:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Xiaojun Wang, Dongguan, CN;

Xinye Yang, Dongguan, CN;

Junwen Wu, Dongguan, CN;

Shaohui Xiong, Dongguan, CN;

Shengqiang Pan, Dongguan, CN;

Shengtian Cao, Dongguan, CN;

Yingjun Zhang, Dongguan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/044 (2006.01); C07D 491/056 (2006.01); A61K 31/4164 (2006.01); A61P 9/04 (2006.01); A61K 31/4353 (2006.01); A61P 15/00 (2006.01); A61P 5/50 (2006.01); A61P 9/12 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61K 31/42 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 491/044 (2013.01); A61K 31/4164 (2013.01); A61K 31/42 (2013.01); A61K 31/4353 (2013.01); A61P 5/50 (2018.01); A61P 7/02 (2018.01); A61P 9/04 (2018.01); A61P 9/10 (2018.01); A61P 9/12 (2018.01); A61P 15/00 (2018.01); C07D 491/056 (2013.01); C07D 491/107 (2013.01);
Abstract

A nitrogen-containing tricyclic compound which acts as modulator of FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the use of the compound for the treatment of disease and/or condition mediated by FXR are described. And a pharmaceutical composition containing the compound disclosed herein and a method of treatment of disease and/or condition mediated by FXR comprising administering the compound or the pharmaceutical composition thereof are also described.


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