The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Aug. 19, 2015
Applicants:

Shanghai Haihe Pharmaceutical Co., Ltd., Shanghai, CN;

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Inventors:

Meiyu Geng, Shanghai, CN;

Lei Liu, Shanghai, CN;

Lei Jiang, Shanghai, CN;

Min Huang, Shanghai, CN;

Chuantao Zha, Shanghai, CN;

Jing Ai, Shanghai, CN;

Lei Wang, Shanghai, CN;

Jianhua Cao, Shanghai, CN;

Jian Ding, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 231/56 (2006.01); C07D 519/00 (2006.01); C07D 401/12 (2006.01); C07D 471/04 (2006.01); C07D 403/12 (2006.01); C07D 498/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 417/12 (2006.01); A61K 31/416 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/416 (2013.01); A61K 31/496 (2013.01); C07D 231/56 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides an indazole compound as a FGFR kinase inhibitor, preparation and use thereof. Specifically, the present invention provides a compound represented by formula (I), wherein the definitions of each group are described in the specification. The compound of the present invention has good FGFR kinase-inhibiting activity, and can be used in preparing a series of medicines for treating FGFR kinase activity related diseases.


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