The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Sep. 22, 2016
Applicant:
Gb005, Inc., San Diego, CA (US);
Inventors:
Assignee:
GB005, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/12 (2006.01); A61P 37/00 (2006.01); A61P 31/12 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61K 47/02 (2006.01); A61K 47/16 (2006.01); C07D 235/32 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); A61K 47/02 (2013.01); A61K 47/16 (2013.01); A61P 29/00 (2018.01); A61P 31/12 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 235/32 (2013.01); C07D 409/14 (2013.01);
Abstract
The present invention relates to a novel family of covalent kinases inhibitors. Compounds of this class have been found to have inhibitory activity against members of the Tec kinase family, particularly ITK, BTK, BMX, Tec and/or RLK. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvate of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof and its use in therapy.