The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Apr. 13, 2016
Applicant:
Eisai R&d Management Co., Ltd., Tokyo, JP;
Inventors:
George Moniz, Cambridge, MA (US);
Kristen Sanders, Gilmanton, NH (US);
Arani Chanda, Andover, MA (US);
Kenshi Yoshida, Tsukuba, JP;
Assignee:
Eisai R&D Management Co., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/505 (2013.01);
Abstract
A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.