The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Jan. 25, 2016
Applicants:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Uab Research Foundation, Birmingham, AL (US);
Inventors:
W. Todd Lowther, Pfafftown, NC (US);
Ross P. Holmes, Birmingham, AL (US);
Daniel Yohannes, Winston-Salem, NC (US);
Assignees:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
UAB Research Foundation, Birmingham, AL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/38 (2006.01); C07C 229/48 (2006.01); C07D 233/90 (2006.01); C07D 307/24 (2006.01); C07D 307/68 (2006.01); C07C 62/02 (2006.01); C07C 62/24 (2006.01); C07C 59/11 (2006.01);
U.S. Cl.
CPC ...
C07C 229/48 (2013.01); C07C 59/11 (2013.01); C07C 62/02 (2013.01); C07C 62/24 (2013.01); C07D 233/90 (2013.01); C07D 307/24 (2013.01); C07D 307/68 (2013.01); C07D 333/38 (2013.01); C07C 2601/08 (2017.05);
Abstract
Provided herein are compounds of Formula (I), Formula (II), and Formula (III), and compositions comprising the same, as well as methods of use thereof for controlling or inhibiting the formation of calcium oxalate kidney stones, inhibiting the production of glyoxylate and/or oxalate, and/or inhibiting hydroxyproline dehydrogenase (HYPDH).