The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Nov. 20, 2017
Applicants:

Paladin Labs Inc., Montreal, CA;

Paladin Labs Europe Limited, Dublin, IE;

Paladin Labs (Barbados) Inc., Hastings, Christ Church, BB;

Inventors:

Francois Ravenelle, Montreal, CA;

Sandra Gori, Montreal, CA;

David Lessard, Montreal, CA;

Laibin Luo, Pierrefonds, CA;

Dorothee Le Garrec, Montreal, CA;

Damon Smith, Saint-Laurent, CA;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 9/19 (2006.01); A61K 31/08 (2006.01); A61K 31/47 (2006.01); A61K 47/32 (2006.01); A61K 31/05 (2006.01); A61J 3/02 (2006.01); A61K 31/085 (2006.01); B01F 3/08 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61J 3/02 (2013.01); A61K 9/0019 (2013.01); A61K 9/0095 (2013.01); A61K 9/1075 (2013.01); A61K 9/19 (2013.01); A61K 31/05 (2013.01); A61K 31/08 (2013.01); A61K 31/085 (2013.01); A61K 31/47 (2013.01); A61K 47/32 (2013.01); B01F 3/088 (2013.01); B01F 2003/0884 (2013.01);
Abstract

The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.


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