The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Feb. 11, 2013
Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Markus Weigandt, Mannheim, DE;

Senta Voss, Mainz, DE;

Tobias Miller, Muenster, DE;

Achim Goepferich, Sinzing, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2017.01); A61K 47/32 (2006.01); A61K 9/14 (2006.01); A61K 31/573 (2006.01); A61K 31/4375 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/14 (2013.01); A61K 31/4375 (2013.01); A61K 31/573 (2013.01); A61K 47/32 (2013.01);
Abstract

The present invention relates to a novel process for the production of nanoparticles laden with active compounds and to the use thereof as medicaments. The process for the production of nanoparticles comprises the steps (a) dissolution of at least one active compound and at least one polymer in an organic solvent, (b) mixing of the solution prepared in step (a) with an aqueous phase, (c) evaporation of the organic solvent, (d) purification of the nanoparticles laden with active compound obtained in step (c) by means of dialysis against aqueous dialysis solution comprising the same active compound.


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