The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
May. 29, 2018
Applicants:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Emory University, Atlanta, GA (US);
Inventors:
Keith A. Reimann, Marblehead, MA (US);
Rijian Wang, Saugus, MA (US);
Christian P. Larsen, Atlanta, GA (US);
Assignees:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/13 (2006.01); C12N 15/12 (2006.01); C12N 15/63 (2006.01); A61K 39/395 (2006.01); A61K 38/13 (2006.01); A61K 45/06 (2006.01); A61K 31/436 (2006.01); C07K 16/28 (2006.01); A61P 37/06 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/436 (2013.01); A61K 38/13 (2013.01); A61K 39/39541 (2013.01); A61K 45/06 (2013.01); A61P 37/06 (2018.01); C07K 16/18 (2013.01); C07K 16/2866 (2013.01); C07K 16/2875 (2013.01); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/76 (2013.01); Y02A 50/386 (2018.01); Y02A 50/41 (2018.01); Y02A 50/412 (2018.01); Y02A 50/414 (2018.01); Y02A 50/423 (2018.01);
Abstract
The present invention relates to antibodies specific for a particular epitope on CD40 and antibodies that bind CD40 and have particular functional characteristics. The present invention also relates to fragments of these antibodies, uses of the antibodies for reduction or treatment of transplant rejection and graft-versus-host disease, and methods for making the antibodies.