The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Dec. 13, 2013
Applicants:

Duke University, Durham, NC (US);

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Barton F. Haynes, Durham, NC (US);

Hua-Xin Liao, Durham, NC (US);

Li-Hua Ping, Chapel Hill, NC (US);

Ronald Swanstrom, Chapel Hill, NC (US);

Beatrice H. Hahn, Philadelphia, PA (US);

George M. Shaw, Philadelphia, PA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); C07K 16/10 (2006.01); A61K 39/108 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/0005 (2013.01); A61K 39/0258 (2013.01); C07K 16/1063 (2013.01); A61K 2039/53 (2013.01); A61K 2039/58 (2013.01); C12N 2740/16034 (2013.01); C12N 2740/16134 (2013.01);
Abstract

The present invention relates, in general, to an immunogen for HIV vaccination and, in particular, to a method of inducing the production of protective anti-HIV antibodies by targeting B cell germline and clone intermediates using a combination of HIV envelope and non-HIV immunogens. The invention also relates to compositions suitable for use in such a method.


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