The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Sep. 03, 2015
Bavarian Nordic A/s, Kvistgaard, DK;
Janssen Vaccines & Prevention B.v., Leiden, NL;
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Ariane Volkmann, Andechs, DE;
Robin Steigerwald, Munich, DE;
Ulrike Dirmeier, Starnberg, DE;
Benoit Christophe Stephan Callendret, Leiden, NL;
Macaya Julie Douoguih, Leiden, NL;
Lucy A. Ward, Silver Spring, MD (US);
Bavarian Nordic A/S, Kvistgaard, DK;
Janssen Vaccines & Prevention B.V., Leiden, NL;
The United States of America, as represented by The Secretary, Department of Health and Human Services, Bethesda, MD (US);
Abstract
Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime and an adenovirus vector as a boost and is characterized by a high level of antibody response specific to the immunogen, and an enhanced cellular immune response. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.