The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2020
Filed:
Jan. 24, 2017
Applicants:
Technion Research & Development Foundation Limited, Haifa, IL;
Rambam Med-tech Ltd., Haifa, IL;
Inventors:
Shira Toledano, Haifa, IL;
Ofra Kessler, Haifa, IL;
Gera Neufeld, Haifa, IL;
Yoreh Barak, Moshav Yodfat, IL;
Yelena Mumblat, Haifa, IL;
Assignees:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD., Haifa, IL;
RAMBAM MED-TECH LTD., Haifa, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 9/0048 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates, according to some embodiments, method of treating eye diseases, such as AMD by administering Semaphorin 3C (Sema3C) or a variant thereof having amino acid modifications at furin-like pro-protein convertase cleavage sites, rendering these sites resistant to cleavage.