The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2020

Filed:

Jul. 25, 2016
Applicants:

Shanghai Haiyan Pharmaceutical Technology Co., Ltd., Shanghai, CN;

Yangtze River Pharmaceutical Group Co., Ltd., Jiangsu, CN;

Inventors:

Jiong Lan, Shanghai, CN;

Taotao Jiang, Shanghai, CN;

Daofei Li, Shanghai, CN;

Xing Liu, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/506 (2006.01); A61P 35/00 (2006.01); A61K 31/4468 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4468 (2013.01); A61K 31/506 (2013.01); C07D 401/14 (2013.01);
Abstract

Provided is an EGFR inhibitor and a pharmaceutically acceptable salt and a polymorph thereof, and a use thereof. In particular, provided is a polymorph, a pharmaceutically acceptable salt or a prodrug of N-(2-(4-(dimethylamino)piperid-1-yl)-5-(5-fluoro-4-(1-methyl-1H-pyrazol-4-yl) pyrimidin-2-ylamino)-4-methoxy phenyl) acrylamide. In addition, also provided is a pharmaceutical composition containing the inhibitor and a use thereof.


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