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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10561642 B1

PDFFull Text
Date of Patent:
Feb. 18, 2020

Filed:

Dec. 28, 2017

Treatment of zika virus infections using alpha-glucosidase inhibitors

Applicant:

Florida State University Research Foundation, Inc., Tallahassee, FL (US);

Inventors:

Eric Holmes, Tallahassee, FL (US);

Gary Ostrander, Tallahassee, FL (US);

Assignee:

FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC., Tallahassee, FL (US);

Attorney:

Saliwanchik, Lloyd & Eisenschenk

Primary Examiner:

Shengjun Wang

Int. Cl.
CPC ...
A61K 31/445 (2006.01); A61K 31/44 (2006.01); A61K 31/437 (2006.01); A61K 31/33 (2006.01); C07D 401/02 (2006.01); A61K 47/60 (2017.01); A61P 31/14 (2006.01); A61K 9/127 (2006.01); A61K 45/06 (2006.01); C12P 17/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 9/127 (2013.01); A61K 31/33 (2013.01); A61K 45/06 (2013.01); A61K 47/60 (2017.08); A61P 31/14 (2018.01); C07D 401/02 (2013.01); C12P 17/12 (2013.01); Y02A 50/391 (2018.01);
Abstract

The present invention concerns the use of castanospermine or other alpha-glucosidase inhibitors for the treatment or prevention of Zika virus infections. Aspects of the invention include methods for treating or preventing Zika virus infection by administering an alpha-glucosidase inhibitor (e.g., an alpha-glucosidase I inhibitor) to a subject in need thereof; methods for inhibiting a Zika virus infection in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits for treating or preventing Zika virus infection.

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